“Mania is, as Leite described, neon. If I am full-blown manic, I am All; I am the Greatest Writer Who Ever Lived, I am a Deity and, as such, require My Pronouns and Titles to be capitalized. I rive skulls, rend nature, exert Myself upon the universe, Intelligence and Sex and Creativity, a Perfect Creature, Napoleon, immune to even heat-death, My mind red-shifting, driven by murmuring voices which I can hear but never make out. I am a Run-On Sentence, a Living James Joyce Passage, and I file essays with 386 word lede sentences, which are, really, as apt a metaphor as I am able to offer, a truly definite porthole, in My Indomitable Opinion; I am Ego, Great and Powerful and Right Ego, gloriously and deliriously thrilled with Me, Myself, the complete and utter inverse of bitter depression, I’m not good enough, not smart enough, not pretty enough, flipped and reversed and shot screaming up in to the night like a bullet, a Catherine Wheel, a cruise missile, a Saturn V, the Immolating Flight of the Wendigo, the very thoughts and prayers and animus of the Earth and creation itself, King of the Towering Peak with tears lashing My eyes, and everything laid out before Me, for Me, to be manipulated by Me; I am Galactus.”
“While at Lawrence Academy in Groton, Massachusetts, Marnell is introduced to Ritalin and the entire trajectory of her life changes. Armed with a methylphenidate prescription, her grades soar, along with her social status. The performance-enhanced work/play dichotomy first established at Lawrence is repeated throughout the rest of the book, throughout the rest of her career; it is the speed which helps her rip through the hallowed halls of Condé Nast like garden shears through satin, pushes her into parties past dawn, sends her careening about the streets of Alphabet City, fitting in to exceptional designer jeans as she chases more drugs, work and people.
The image of the addict as hopelessly in the gutter, completely incapable of functioning, is torn asunder. She has crippling depressive periods, of course, wherein she does nothing for days, weeks, months, but Marnell is a voltaic little bee for much of her memoir, omnipresent around Magazine World. It would be impossible to deny her work ethic, drug-derived or not; Marnell’s desire to work in magazines and publishing is a constant lodestar, even if one being navigated while on a particularly unstable fuel source.”
“In Fond Du Lac, Wis., Russell introduces us to Tim Friede, who has taken man’s desire for inviolability to its intoxicating extreme, purging himself of even the most recognized and acknowledged of flaws: our susceptibility to snake venom. Friede is a practitioner of mithridatism, named for the Poison King, Mithradates VI, who immunized himself so effectively against the various foul defenses of nature that even Rome’s best poisoners could not make him sick. Friede voluntarily envenomates himself—when Russell sees him, via snake-and-fang—to inoculate against the serpents: an African water cobra, even a black mamba does not kill Friede. When Russell leaves him, he is hunched pitifully over a space heater alone, limbs still rigid.”